The verifiable place to buy research peptides · Free shipping over $150
0

Research Reference · Tissue Repair Blend

BB (BPC-157 & TB-500)

A two-peptide research blend of BPC-157 and TB-500 — the pairing known in research circles as the “Wolverine” stack — studied through its components in preclinical repair models.

Last reviewed September 2026 7 peer-reviewed sources 3-minute read

At a glance

BB is a research blend of two peptides — BPC-157 and TB-500, 10 mg each — the pairing known in research circles as the “Wolverine” stack. Both are among the most-studied repair peptides and are often examined together. No study of the blend itself has been published: the evidence belongs to each component and is mostly preclinical.

TypeTwo-peptide blend (20 mg)
ComponentsBPC-157 10 mg · TB-500 10 mg
Evidence stageComponent studies (preclinical)
Human dataNone for the blend

What it’s studied for

Tendon & soft tissue

BPC-157 increased tendon-cell outgrowth, survival and migration; reviews cover muscle, tendon and ligament models. 2,3

Cell & animal

Wound closure

Thymosin beta-4 sped wound closure in rats; BPC-157 has its own wound-healing literature. 5,1

Animal

Cell migration

Thymosin beta-4 controls actin, the protein cells use to move. 6,4

Cell

Blood-vessel formation

BPC-157 activated the VEGFR2 pathway behind new vessel growth. 7

Cell & animal

BB

BB (20mg) · $79.99

Third-party tested · batch-matched COA · research use only

View BB BB COAsUsage guide

How it works

BB combines two peptides with different, complementary roles in repair models. BPC-157 is studied for repair signaling and new blood-vessel growth through the VEGFR2 pathway, 7 and in culture it increased tendon-cell outgrowth, survival and migration. 2

TB-500 (thymosin beta-4) controls actin — the protein cells use to move — and sped wound closure in rats. 6,5

Researchers pair them to study repair signaling and cell movement in the same model. No study of the combined blend has been published, so each component’s evidence should be read on its own terms. 3,4

Related research

BPC-157Component TB-500Component GLOW (Three-Peptide Blend)BB + GHK-Cu KLOW (Four-Peptide Blend)GLOW + KPV

Frequently asked questions

What is in BB?
BPC-157 (10 mg) and TB-500 (10 mg) in one vial — 20 mg of total peptide.
Why is it called the “Wolverine” stack?
It is a research-community nickname for the BPC-157 + TB-500 pairing, a nod to how often the two appear together in repair studies.
Has the BB blend itself been studied?
No published study tests the blend. The research belongs to BPC-157 and thymosin beta-4 individually.
How is BB different from GLOW and KLOW?
GLOW adds GHK-Cu (50 mg) to the same pairing; KLOW adds GHK-Cu and KPV.
How is each batch verified?
The batch certificate of analysis measures each component separately and is published by batch number on our COA page.

Identifiers

Components BPC-157 (10 mg) + TB-500 (10 mg)
Total peptide 20 mg per vial
BPC-157 C62H98N16O22 · CAS 137525-51-0 · PubChem CID 9941957
TB-500 Thymosin beta-4 / its 17–23 fragment — see the TB-500 page
Batch testing Each component quantified separately on the COA
Supplied as Lyophilized (freeze-dried) powder

Component identifiers checked against PubChem.

Research timeline

  1. 1999Thymosin beta-4 speeds wound closure in rats. 5
  2. 2005Review of thymosin beta-4 as an actin-binding repair protein. 6
  3. 2011BPC-157 increases tendon-cell outgrowth, survival and migration. 2
  4. 2017BPC-157’s VEGFR2 blood-vessel mechanism is described. 7
  5. 2019Review of BPC-157 in soft-tissue healing. 3
  6. 2021Reviews of BPC-157 in wound healing 1 and of thymosin beta-4. 4

Key studies

StudyModelWhat it found
Malinda 1999 5 Rat + cell (Tβ4) Faster wound closure; more skin-cell migration.
Chang 2011 2 Cell (BPC-157) More tendon-cell outgrowth, survival and migration.
Hsieh 2017 7 Cell + rat (BPC-157) VEGFR2–Akt–eNOS activation; better blood-flow recovery.
Gwyer 2019 3 Review (BPC-157) Musculoskeletal soft-tissue healing evidence and mechanisms.

Sources

  1. Stable Gastric Pentadecapeptide BPC 157 and Wound Healing. Seiwerth S, et al. Front Pharmacol, 2021. Free full textReview
  2. The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. Chang CH, et al. J Appl Physiol, 2011.
  3. Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing. Gwyer D, et al. Cell Tissue Res, 2019. Review
  4. Progress on the Function and Application of Thymosin β4. Xing Y, et al. Front Endocrinol (Lausanne), 2021. Free full textReview
  5. Thymosin beta4 accelerates wound healing. Malinda KM, et al. J Invest Dermatol, 1999.
  6. Thymosin beta4: actin-sequestering protein moonlights to repair injured tissues. Goldstein AL, et al. Trends Mol Med, 2005. Review
  7. Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation. Hsieh MJ, et al. J Mol Med, 2017.
For Research Use Only. This page summarizes published scientific research for educational purposes. It is not medical advice and does not promote, recommend, or describe any human or animal use. Products referenced are sold strictly for laboratory research and are not for human consumption.

Last reviewed September 2026 by Midwest Compounds. Every source above was checked against its original publication.